Publications

Links to all our papers may be found on Google Scholar

2024

  1. Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis
    KD Whitley, J Grimshaw, DM Roberts, and 3 more authors
    Nature Microbiology, 2024
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2023

  1. Self-organisation of mortal filaments: the role of FtsZ treadmilling in bacterial division ring formation
    Christian Vanhille Campos, Kevin D Whitley, Philipp Radler, and 3 more authors
    bioRxiv, 2023
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  2. Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis
    Stuart Middlemiss, David M Roberts, James Grimshaw, and 6 more authors
    bioRxiv, 2023
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  3. A one-track model for spatiotemporal coordination of Bacillus subtilis septal cell wall synthesis
    Kevin D Whitley, James Grimshaw, Eleni Karinou, and 2 more authors
    bioRxiv, 2023
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  4. Transertion and cell geometry organize the Escherichia coli nucleoid during rapid growth
    Christoph Spahn, Stuart Middlemiss, Estibaliz Gómez-de-Mariscal, and 4 more authors
    bioRxiv, 2023
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  5. Complement-mediated killing of bacteria by mechanical destabilization of the cell envelope
    Georgina Benn, Christian Bortolini, David M Roberts, and 3 more authors
    bioRxiv, 2023
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2022

  1. High-resolution imaging of bacterial spatial organization with vertical cell imaging by nanostructured immobilization (VerCINI)
    Kevin D Whitley, Stuart Middlemiss, Calum Jukes, and 2 more authors
    Nature Protocols, 2022
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  2. Open microscopy in the life sciences: quo vadis?
    Johannes Hohlbein, Benedict Diederich, Barbora Marsikova, and 5 more authors
    Nature Methods, 2022
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  3. DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches
    Christoph Spahn, Estibaliz Gómez-de-Mariscal, Romain F Laine, and 8 more authors
    Communications Biology, 2022
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2021

  1. FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
    Kevin D Whitley, Calum Jukes, Nicholas Tregidgo, and 6 more authors
    Nature communications, 2021
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  2. Democratising deep learning for microscopy with ZeroCostDL4Mic
    Lucas Chamier, Romain F Laine, Johanna Jukkala, and 8 more authors
    Nature communications, 2021
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2020

  1. Geometric principles underlying the proliferation of a model cell system
    Ling Juan Wu, Seoungjun Lee, Sungshic Park, and 4 more authors
    Nature communications, 2020
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  2. Virtual-SMLM, a virtual environment for real-time interactive SMLM acquisition
    J Griffié, TA Pham, C Sieben, and 6 more authors
    bioRxiv, 2020
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2019

  1. Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software
    Daniel Sage, Thanh-An Pham, Hazen Babcock, and 8 more authors
    Nature methods, 2019
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  2. Movement dynamics of divisome proteins and PBP2x: FtsW in cells of Streptococcus pneumoniae
    Amilcar J Perez, Yann Cesbron, Sidney L Shaw, and 8 more authors
    Proceedings of the National Academy of Sciences, 2019
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2018

  1. Probing the mechanistic principles of bacterial cell division with super-resolution microscopy
    Seamus Holden
    Current opinion in microbiology, 2018
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  2. Constriction rate modulation can drive cell size control and homeostasis in C. crescentus
    Ambroise Lambert, Aster Vanhecke, Anna Archetti, and 6 more authors
    Iscience, 2018
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2017

  1. Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division
    Alexandre W Bisson-Filho, Yen-Pang Hsu, Georgia R Squyres, and 8 more authors
    Science, 2017
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2016

  1. Super-resolution fight club
    Seamus Holden, and Daniel Sage
    Nature Photonics, 2016
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  2. Functional dichotomy and distinct nanoscale assemblies of a cell cycle-controlled bipolar zinc-finger regulator
    Johann Mignolet, Seamus Holden, Matthieu Berge, and 5 more authors
    Elife, 2016
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  3. Modularity and determinants of a (bi-) polarization control system from free-living and obligate intracellular bacteria
    Matthieu Berge, Sebastien Campagne, Johann Mignolet, and 5 more authors
    Elife, 2016
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2015

  1. PALMsiever: a tool to turn raw data into results for single-molecule localization microscopy
    Thomas Pengo, Seamus J Holden, and Suliana Manley
    Bioinformatics, 2015
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  2. Correction of a depth-dependent lateral distortion in 3D super-resolution imaging
    Lina Carlini, Seamus J Holden, Kyle M Douglass, and 1 more author
    PLoS One, 2015
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2014

  1. Photoactivated localization microscopy for cellular imaging
    Paulina Achurra, Seamus Holden, Thomas Pengo, and 1 more author
    Super-Resolution Microscopy Techniques in the Neurosciences, 2014
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  2. High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization
    Seamus J Holden, Thomas Pengo, Karin L Meibom, and 3 more authors
    Proceedings of the National Academy of Sciences, 2014
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  3. FALCON: fast and unbiased reconstruction of high-density super-resolution microscopy data
    Junhong Min, Cédric Vonesch, Hagai Kirshner, and 6 more authors
    Scientific reports, 2014
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  4. 3D high-density localization microscopy using hybrid astigmatic/biplane imaging and sparse image reconstruction
    Junhong Min, Seamus J Holden, Lina Carlini, and 3 more authors
    Biomedical optics express, 2014
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2013

  1. Multiscale Spatial Organization of RNA Polymerase in Escherichia coli
    Ulrike Endesfelder, Kieran Finan, Seamus J Holden, and 3 more authors
    Biophysical Journal, 2013
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  2. Optimisation and control of sampling rate in localisation microscopy
    S Holden, Thomas Pengo, and Suliana Manley
    In 10th International Conference on Sampling Theory and Applications, 2013
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2011

  1. DAOSTORM: an algorithm for high-density super-resolution microscopy
    Seamus J Holden, Stephan Uphoff, and Achillefs N Kapanidis
    Nature Methods, 2011
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  2. Identifying molecular dynamics in single-molecule FRET experiments with burst variance analysis
    Joseph P Torella, Seamus J Holden, Yusdi Santoso, and 2 more authors
    Biophysical journal, 2011
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  3. Improved methods for sub-diffraction-limit single-molecule fluorescence measurements
    Seamus J Holden
    Oxford University, 2011

2010

  1. Monitoring multiple distances within a single molecule using switchable FRET
    Stephan Uphoff, Seamus J Holden, Ludovic Le Reste, and 4 more authors
    Nature Methods, 2010
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  2. Single-Molecule DNA Biosensors for Protein and Ligand Detection
    Konstantinos Lymperopoulos, Robert Crawford, Joseph P Torella, and 4 more authors
    Angewandte Chemie International Edition, 2010
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  3. Defining the Limits of Single-Molecule FRET Resolution in TIRF Microscopy
    Seamus J Holden, Stephan Uphoff, Johannes Hohlbein, and 4 more authors
    Biophysical Journal, 2010
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2009

  1. Alternating-Laser Excitation and Pulsed-Interleaved Excitation of Single Molecules
    Seamus J Holden, and Achillefs N Kapanidis
    Single Particle Tracking and Single Molecule Energy Transfer, 2009
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  2. Single-molecule FRET: methods and biological applications
    Ling Chin Hwang, Johannes Hohlbein, Seamus J Holden, and 1 more author
    Handbook of single-molecule biophysics, 2009
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