Welcome to the Holden Lab website!

We are interdisciplinary scientists who study bacterial cell biology and biophysics using super-resolution microscopy and other advanced imaging methods. Our primary biological focus is how bacteria remodel their cell wall, which is one of the most important targets​ for antibiotics.

We are based in the Interdisciplinary Biosciences Research Building, in the School of Life Sciences, University of Warwick, near Coventry, UK.

Key research themes

• Mechanistic principles of bacterial cell wall remodelling
• Single molecule & super-resolution microscopy
• Open source scientific software and hardware

Open science resources

• Information about how to obtain and use VerCINI chips which we developed for microscopy of vertically immobilised bacteria can be found here.
• Software made by our lab can be found on the HoldenLab GitHub
• Information about alternatives to ThermoFisher GeneFrames for bacterial timelapse microscopy can be found here