Molecular mechanisms of cell wall synthesis
The bacterial cell wall is a large mesh-like material composed of peptidoglycan: long cable-like glycan polymers, linked together by peptide crosslinks. We are interested in understanding how cell wall synthesis enzymes make peptidoglycan at the molecular level.
We are using in vitro single molecule fluorescence methods to investigate this question.
People
- Jack Stone, Senior Reseach Technician, Biochemist (joint with Roper lab).
- Kateryna Nitsenko, PDRA, Biophysicist.